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Neonatal mice possess two phenotypically and functionally distinct lung-migratory CD103+ dendritic cell populations following respiratory infection

The CD103+ subset of lung migratory dendritic cells (DCs) plays an important role in the generation of CD8+ T cell responses following respiratory infection. Here, we demonstrate that the dependence on CD103+ DCs for stimulation of RSV-specific T cells is both epitope and age-dependent. CD103+ DCs i...

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Detalles Bibliográficos
Autores principales: Ruckwardt, Tracy J, Morabito, Kaitlyn M, Bar-Haim, Erez, Nair, Deepika, Graham, Barney S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628111/
https://www.ncbi.nlm.nih.gov/pubmed/28378805
http://dx.doi.org/10.1038/mi.2017.28