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Regulatory T-cell heterogeneity and the cancer immune response

The frequency of circulating or tumour-infiltrating regulatory T cells (Tregs) has been associated with poor patient survival in many cancers including breast, melanoma and lung. It has been hypothesised that Tregs impact the anti-tumour function of effector T cells, resulting in worse outcomes for...

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Detalles Bibliográficos
Autores principales: Ward-Hartstonge, Kirsten A, Kemp, Roslyn A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628269/
https://www.ncbi.nlm.nih.gov/pubmed/28983402
http://dx.doi.org/10.1038/cti.2017.43