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Casein kinase 2 is a critical determinant of the balance of Th17 and Treg cell differentiation

Th17 cells promote inflammatory reactions, whereas regulatory T (Treg) cells inhibit them. Thus, the Th17/Treg cell balance is critically important in inflammatory diseases. However, the molecular mechanisms underlying this balance are unclear. Here, we demonstrate that casein kinase 2 (CK2) is a cr...

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Detalles Bibliográficos
Autores principales: Jang, Sung Woong, Hwang, Soo Seok, Kim, Hyeong Su, Lee, Keoung Oh, Kim, Min Kyung, Lee, Wonyong, Kim, Kiwan, Lee, Gap Ryol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628272/
https://www.ncbi.nlm.nih.gov/pubmed/28883547
http://dx.doi.org/10.1038/emm.2017.132