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Casein kinase 2 is a critical determinant of the balance of Th17 and Treg cell differentiation
Th17 cells promote inflammatory reactions, whereas regulatory T (Treg) cells inhibit them. Thus, the Th17/Treg cell balance is critically important in inflammatory diseases. However, the molecular mechanisms underlying this balance are unclear. Here, we demonstrate that casein kinase 2 (CK2) is a cr...
Autores principales: | Jang, Sung Woong, Hwang, Soo Seok, Kim, Hyeong Su, Lee, Keoung Oh, Kim, Min Kyung, Lee, Wonyong, Kim, Kiwan, Lee, Gap Ryol |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628272/ https://www.ncbi.nlm.nih.gov/pubmed/28883547 http://dx.doi.org/10.1038/emm.2017.132 |
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