Upregulation of FcγRIIB by resveratrol via NF-κB activation reduces B-cell numbers and ameliorates lupus

Resveratrol, an anti-inflammatory agent, can inhibit pro-inflammatory mediators by activating Sirt1, which is a class III histone deacetylase. However, whether resveratrol can regulate inhibitory or anti-inflammatory molecules has been less studied. FcγRIIB, a receptor for IgG, is an essential inhib...

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Detalles Bibliográficos
Autores principales: Jhou, Jyun-Pei, Chen, Se-Jie, Huang, Ho-Yin, Lin, Wan-Wan, Huang, Duen-Yi, Tzeng, Shiang-Jong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628277/
https://www.ncbi.nlm.nih.gov/pubmed/28960214
http://dx.doi.org/10.1038/emm.2017.144

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628277/
https://www.ncbi.nlm.nih.gov/pubmed/28960214
http://dx.doi.org/10.1038/emm.2017.144

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