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Human TorsinA can function in the yeast cytosol as a molecular chaperone

TorsinA (TorA) is an AAA+ (ATPases associated with diverse cellular activities) ATPase linked to dystonia type 1 (DYT1), a neurological disorder that leads to uncontrollable muscular movements. Although DYT1 is linked to a 3 bp deletion in the C-terminus of TorA, the biological function of TorA rema...

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Detalles Bibliográficos
Autores principales: Adam, Ilectra, Jossé, Lyne, Tuite, Mick F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628414/
https://www.ncbi.nlm.nih.gov/pubmed/28871039
http://dx.doi.org/10.1042/BCJ20170395