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Abiraterone acetate plus LHRH therapy versus abiraterone acetate while sparing LHRH therapy in patients with progressive, metastatic and chemotherapy-naïve, castration-resistant prostate cancer (SPARE): study protocol for a randomized controlled trial

BACKGROUND: The value of continuation of luteinizing hormone-releasing hormone (LHRH) therapy in castration-resistant prostate cancer (CRPC) remains controversial and clear evidence is lacking. Argumentation for cessation of LHRH therapy is the prolonged suppression of testosterone levels after the...

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Detalles Bibliográficos
Autores principales: Ohlmann, Carsten-Henning, Jäschke, Michelle, Jaehnig, Peter, Krege, Susane, Gschwend, Jürgen, Rexer, Heidrun, Stöckle, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628432/
https://www.ncbi.nlm.nih.gov/pubmed/28978327
http://dx.doi.org/10.1186/s13063-017-2195-x