Lysosome trafficking is necessary for EGF-driven invasion and is regulated by p38 MAPK and Na+/H+ exchangers

BACKGROUND: Tumor invasion through a basement membrane is one of the earliest steps in metastasis, and growth factors, such as Epidermal Growth Factor (EGF) and Hepatocyte Growth Factor (HGF), stimulate this process in a majority of solid tumors. Basement membrane breakdown is one of the hallmarks o...

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Detalles Bibliográficos
Autores principales: Dykes, Samantha S., Steffan, Joshua J., Cardelli, James A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628462/
https://www.ncbi.nlm.nih.gov/pubmed/28978320
http://dx.doi.org/10.1186/s12885-017-3660-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628462/
https://www.ncbi.nlm.nih.gov/pubmed/28978320
http://dx.doi.org/10.1186/s12885-017-3660-3

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