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Soluble polymorphic bank vole prion proteins induced by co-expression of quiescin sulfhydryl oxidase in E. coli and their aggregation behaviors
BACKGROUND: The infectious prion protein (PrP(Sc) or prion) is derived from its cellular form (PrP(C)) through a conformational transition in animal and human prion diseases. Studies have shown that the interspecies conversion of PrP(C) to PrP(Sc) is largely swayed by species barriers, which is main...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628483/ https://www.ncbi.nlm.nih.gov/pubmed/28978309 http://dx.doi.org/10.1186/s12934-017-0782-x |