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Soluble polymorphic bank vole prion proteins induced by co-expression of quiescin sulfhydryl oxidase in E. coli and their aggregation behaviors

BACKGROUND: The infectious prion protein (PrP(Sc) or prion) is derived from its cellular form (PrP(C)) through a conformational transition in animal and human prion diseases. Studies have shown that the interspecies conversion of PrP(C) to PrP(Sc) is largely swayed by species barriers, which is main...

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Detalles Bibliográficos
Autores principales: Abskharon, Romany, Dang, Johnny, Elfarash, Ameer, Wang, Zerui, Shen, Pingping, Zou, Lewis S., Hassan, Sedky, Wang, Fei, Fujioka, Hisashi, Steyaert, Jan, Mulaj, Mentor, Surewicz, Witold K., Castilla, Joaquín, Wohlkonig, Alexandre, Zou, Wen-Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628483/
https://www.ncbi.nlm.nih.gov/pubmed/28978309
http://dx.doi.org/10.1186/s12934-017-0782-x