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VB-MK-LMF: fusion of drugs, targets and interactions using variational Bayesian multiple kernel logistic matrix factorization

BACKGROUND: Computational fusion approaches to drug-target interaction (DTI) prediction, capable of utilizing multiple sources of background knowledge, were reported to achieve superior predictive performance in multiple studies. Other studies showed that specificities of the DTI task, such as weigh...

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Detalles Bibliográficos
Autores principales: Bolgár, Bence, Antal, Péter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628496/
https://www.ncbi.nlm.nih.gov/pubmed/28978313
http://dx.doi.org/10.1186/s12859-017-1845-z