The caspase-8/RIPK3 signaling axis in antigen presenting cells controls the inflammatory arthritic response

BACKGROUND: Caspase-8 is a well-established initiator of apoptosis and suppressor of necroptosis, but maintains functions beyond cell death that involve suppression of receptor-interacting serine-threonine kinases (RIPKs). A genome-wide association study meta-analysis revealed an SNP associated with...

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Detalles Bibliográficos
Autores principales: Dominguez, Salina, Montgomery, Anna B., Haines, G. Kenneth, Bloomfield, Christina L., Cuda, Carla M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628498/
https://www.ncbi.nlm.nih.gov/pubmed/28978351
http://dx.doi.org/10.1186/s13075-017-1436-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628498/
https://www.ncbi.nlm.nih.gov/pubmed/28978351
http://dx.doi.org/10.1186/s13075-017-1436-4

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