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The caspase-8/RIPK3 signaling axis in antigen presenting cells controls the inflammatory arthritic response
BACKGROUND: Caspase-8 is a well-established initiator of apoptosis and suppressor of necroptosis, but maintains functions beyond cell death that involve suppression of receptor-interacting serine-threonine kinases (RIPKs). A genome-wide association study meta-analysis revealed an SNP associated with...
Autores principales: | Dominguez, Salina, Montgomery, Anna B., Haines, G. Kenneth, Bloomfield, Christina L., Cuda, Carla M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628498/ https://www.ncbi.nlm.nih.gov/pubmed/28978351 http://dx.doi.org/10.1186/s13075-017-1436-4 |
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