In vivo evaluation of cetuximab-conjugated poly(γ-glutamic acid)-docetaxel nanomedicines in EGFR-overexpressing gastric cancer xenografts

Epidermal growth factor receptor (EGFR), upregulated in gastric cancer patients, is an oncogene of interest in the development of targeted cancer nanomedicines. This study demonstrates in silico modeling of monoclonal antibody cetuximab (CET MAb)-conjugated docetaxel (DOCT)-loaded poly(γ-glutamic ac...

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Detalles Bibliográficos
Autores principales: Sreeranganathan, Maya, Uthaman, Saji, Sarmento, Bruno, Mohan, Chethampadi Gopi, Park, In-Kyu, Jayakumar, Rangasamy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628680/
https://www.ncbi.nlm.nih.gov/pubmed/29033568
http://dx.doi.org/10.2147/IJN.S143529

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628680/
https://www.ncbi.nlm.nih.gov/pubmed/29033568
http://dx.doi.org/10.2147/IJN.S143529

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