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The folded k-spectrum kernel: A machine learning approach to detecting transcription factor binding sites with gapped nucleotide dependencies

Understanding the molecular machinery involved in transcriptional regulation is central to improving our knowledge of an organism’s development, disease, and evolution. The building blocks of this complex molecular machinery are an organism’s genomic DNA sequence and transcription factor proteins. D...

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Detalles Bibliográficos
Autores principales: Elmas, Abdulkadir, Wang, Xiaodong, Dresch, Jacqueline M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628859/
https://www.ncbi.nlm.nih.gov/pubmed/28982128
http://dx.doi.org/10.1371/journal.pone.0185570