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Genetic plasticity of the Shigella virulence plasmid is mediated by intra- and inter-molecular events between insertion sequences

Acquisition of a single copy, large virulence plasmid, pINV, led to the emergence of Shigella spp. from Escherichia coli. The plasmid encodes a Type III secretion system (T3SS) on a 30 kb pathogenicity island (PAI), and is maintained in a bacterial population through a series of toxin:antitoxin (TA)...

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Detalles Bibliográficos
Autores principales: Pilla, Giulia, McVicker, Gareth, Tang, Christoph M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629016/
https://www.ncbi.nlm.nih.gov/pubmed/28945748
http://dx.doi.org/10.1371/journal.pgen.1007014