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Genetic plasticity of the Shigella virulence plasmid is mediated by intra- and inter-molecular events between insertion sequences
Acquisition of a single copy, large virulence plasmid, pINV, led to the emergence of Shigella spp. from Escherichia coli. The plasmid encodes a Type III secretion system (T3SS) on a 30 kb pathogenicity island (PAI), and is maintained in a bacterial population through a series of toxin:antitoxin (TA)...
Autores principales: | Pilla, Giulia, McVicker, Gareth, Tang, Christoph M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629016/ https://www.ncbi.nlm.nih.gov/pubmed/28945748 http://dx.doi.org/10.1371/journal.pgen.1007014 |
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