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p53-dependent programmed necrosis controls germ cell homeostasis during spermatogenesis
The importance of regulated necrosis in pathologies such as cerebral stroke and myocardial infarction is now fully recognized. However, the physiological relevance of regulated necrosis remains unclear. Here, we report a conserved role for p53 in regulating necrosis in Drosophila and mammalian sperm...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629030/ https://www.ncbi.nlm.nih.gov/pubmed/28945745 http://dx.doi.org/10.1371/journal.pgen.1007024 |