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p53-dependent programmed necrosis controls germ cell homeostasis during spermatogenesis

The importance of regulated necrosis in pathologies such as cerebral stroke and myocardial infarction is now fully recognized. However, the physiological relevance of regulated necrosis remains unclear. Here, we report a conserved role for p53 in regulating necrosis in Drosophila and mammalian sperm...

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Detalles Bibliográficos
Autores principales: Napoletano, Francesco, Gibert, Benjamin, Yacobi-Sharon, Keren, Vincent, Stéphane, Favrot, Clémentine, Mehlen, Patrick, Girard, Victor, Teil, Margaux, Chatelain, Gilles, Walter, Ludivine, Arama, Eli, Mollereau, Bertrand
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629030/
https://www.ncbi.nlm.nih.gov/pubmed/28945745
http://dx.doi.org/10.1371/journal.pgen.1007024

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