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Formation of a TBX20-CASZ1 protein complex is protective against dilated cardiomyopathy and critical for cardiac homeostasis

By the age of 40, one in five adults without symptoms of cardiovascular disease are at risk for developing congestive heart failure. Within this population, dilated cardiomyopathy (DCM) remains one of the leading causes of disease and death, with nearly half of cases genetically determined. Though g...

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Detalles Bibliográficos
Autores principales: Kennedy, Leslie, Kaltenbrun, Erin, Greco, Todd M., Temple, Brenda, Herring, Laura E., Cristea, Ileana M., Conlon, Frank L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629033/
https://www.ncbi.nlm.nih.gov/pubmed/28945738
http://dx.doi.org/10.1371/journal.pgen.1007011