GATA3 Targets Semaphorin 3B in Mammary Epithelial Cells to Suppress Breast Cancer Progression and Metastasis

Semaphorin 3B (SEMA3B) is a secreted axonal guidance molecule that is expressed during development and throughout adulthood. Recently, SEMA3B has emerged as a tumor suppressor in non-neuronal cells. Here we show that SEMA3B is a direct target of GATA3 transcriptional activity. GATA3 is a key transcr...

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Detalles Bibliográficos
Autores principales: Shahi, Payam, Wang, Chih-Yang, Chou, Jonathan, Hagerling, Catharina, Velozo, Hugo Gonzalez, Ruderisch, Aline, Yu, Ying, Lai, Ming-Derg, Werb, Zena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629104/
https://www.ncbi.nlm.nih.gov/pubmed/28581515
http://dx.doi.org/10.1038/onc.2017.165

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629104/
https://www.ncbi.nlm.nih.gov/pubmed/28581515
http://dx.doi.org/10.1038/onc.2017.165

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