Cargando…
GATA3 Targets Semaphorin 3B in Mammary Epithelial Cells to Suppress Breast Cancer Progression and Metastasis
Semaphorin 3B (SEMA3B) is a secreted axonal guidance molecule that is expressed during development and throughout adulthood. Recently, SEMA3B has emerged as a tumor suppressor in non-neuronal cells. Here we show that SEMA3B is a direct target of GATA3 transcriptional activity. GATA3 is a key transcr...
Autores principales: | Shahi, Payam, Wang, Chih-Yang, Chou, Jonathan, Hagerling, Catharina, Velozo, Hugo Gonzalez, Ruderisch, Aline, Yu, Ying, Lai, Ming-Derg, Werb, Zena |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629104/ https://www.ncbi.nlm.nih.gov/pubmed/28581515 http://dx.doi.org/10.1038/onc.2017.165 |
Ejemplares similares
-
Roles of the immune system in cancer: from tumor initiation to metastatic progression
por: Gonzalez, Hugo, et al.
Publicado: (2018) -
Systematic analysis of the achaete-scute complex-like gene signature in clinical cancer patients
por: Wang, Chih-Yang, et al.
Publicado: (2017) -
Gata-3 and mammary cell fate
por: Naylor, Matthew J, et al.
Publicado: (2007) -
Anoikis resistance in mammary epithelial cells is mediated by semaphorin 7a
por: Rutherford, Taylor R., et al.
Publicado: (2021) -
Single-cell RNA sequencing reveals gene expression signatures of breast cancer-associated endothelial cells
por: Sun, Zhengda, et al.
Publicado: (2017)