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Pharmacokinetic Bioequivalence Studies of an Extended-Release Oxycodone Hydrochloride Tablet in Healthy Japanese Subjects Under Fasting and Fed Conditions Without an Opioid Antagonist

Oxycodone is a semisynthetic opioid used for the treatment of moderate to severe pain. Two separate studies were conducted to assess the pharmacokinetic bioequivalence of a newly formulated oxycodone hydrochloride extended-release tablet to a marketed oxycodone product in Japan under fasting and fed...

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Detalles Bibliográficos
Autores principales: Toyama, Kaoru, Furuie, Hidetoshi, Kuroda, Kana, Ishizuka, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629125/
https://www.ncbi.nlm.nih.gov/pubmed/28516342
http://dx.doi.org/10.1007/s40268-017-0184-x