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Impact of Genetic Polymorphisms on Phenytoin Pharmacokinetics and Clinical Outcomes in the Middle East and North Africa Region

BACKGROUND: Genetic polymorphisms are known to influence outcomes with phenytoin yet effects in the Middle East and North Africa region are poorly understood. OBJECTIVES: The objective of this systematic review was to evaluate the impact of genetic polymorphisms on phenytoin pharmacokinetics and cli...

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Detalles Bibliográficos
Autores principales: Dagenais, Renée, Wilby, Kyle John, Elewa, Hazem, Ensom, Mary H. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629135/
https://www.ncbi.nlm.nih.gov/pubmed/28748348
http://dx.doi.org/10.1007/s40268-017-0195-7