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Identification of Polymorphic Forms of Active Pharmaceutical Ingredient in Low-Concentration Dry Powder Formulations by Synchrotron X-Ray Powder Diffraction

BACKGROUND: The identification of different (pseudo) polymorphs of an active pharmaceutical ingredient in dry powder formulations is of importance during development and entire product lifecycle, e.g., quality control. Whereas determination of polymorphic differences of pure substances is rather eas...

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Detalles Bibliográficos
Autores principales: Egusa, Kenji, Okazaki, Fumiaki, Schiewe, Joerg, Werthmann, Ulrike, Wolkenhauer, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629136/
https://www.ncbi.nlm.nih.gov/pubmed/28905245
http://dx.doi.org/10.1007/s40268-017-0196-6