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Identification of Polymorphic Forms of Active Pharmaceutical Ingredient in Low-Concentration Dry Powder Formulations by Synchrotron X-Ray Powder Diffraction
BACKGROUND: The identification of different (pseudo) polymorphs of an active pharmaceutical ingredient in dry powder formulations is of importance during development and entire product lifecycle, e.g., quality control. Whereas determination of polymorphic differences of pure substances is rather eas...
Autores principales: | Egusa, Kenji, Okazaki, Fumiaki, Schiewe, Joerg, Werthmann, Ulrike, Wolkenhauer, Markus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629136/ https://www.ncbi.nlm.nih.gov/pubmed/28905245 http://dx.doi.org/10.1007/s40268-017-0196-6 |
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