Full hydrodynamic reversibility of the weak dimerization of vancomycin and elucidation of its interaction with VanS monomers at clinical concentration

The reversibility and strength of the previously established dimerization of the important glycopeptide antibiotic vancomycin in four different aqueous solvents (including a medically-used formulation) have been studied using short-column sedimentation equilibrium in the analytical ultracentrifuge a...

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Detalles Bibliográficos
Autores principales: Phillips-Jones, Mary K., Lithgo, Ryan, Dinu, Vlad, Gillis, Richard B., Harding, John E., Adams, Gary G., Harding, Stephen E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629194/
https://www.ncbi.nlm.nih.gov/pubmed/28983082
http://dx.doi.org/10.1038/s41598-017-12620-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629194/
https://www.ncbi.nlm.nih.gov/pubmed/28983082
http://dx.doi.org/10.1038/s41598-017-12620-z

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