The GBAP1 pseudogene acts as a ceRNA for the glucocerebrosidase gene GBA by sponging miR-22-3p

Mutations in the GBA gene, encoding lysosomal glucocerebrosidase, represent the major predisposing factor for Parkinson’s disease (PD), and modulation of the glucocerebrosidase activity is an emerging PD therapy. However, little is known about mechanisms regulating GBA expression. We explored the ex...

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Detalles Bibliográficos
Autores principales: Straniero, Letizia, Rimoldi, Valeria, Samarani, Maura, Goldwurm, Stefano, Di Fonzo, Alessio, Krüger, Rejko, Deleidi, Michela, Aureli, Massimo, Soldà, Giulia, Duga, Stefano, Asselta, Rosanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629250/
https://www.ncbi.nlm.nih.gov/pubmed/28983119
http://dx.doi.org/10.1038/s41598-017-12973-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629250/
https://www.ncbi.nlm.nih.gov/pubmed/28983119
http://dx.doi.org/10.1038/s41598-017-12973-5

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