IFN-α-mediated Base Excision Repair Pathway Correlates with Antiviral Response Against Hepatitis B Virus Infection

Previous studies identified APOBEC deaminases as enzymes targeting hepatitis B virus (HBV) DNA in the nucleus thus affecting its persistence. Interferon (IFN)-α treated chimpanzees and hepatitis C patients showed elevated APOBEC expression. We thus hypothesized that the responses to IFN-α treatment...

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Detalles Bibliográficos
Autores principales: Li, Yong, Xia, Yuchen, Han, Meifang, Chen, Guang, Zhang, Dake, Thasler, Wolfgang E., Protzer, Ulrike, Ning, Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629255/
https://www.ncbi.nlm.nih.gov/pubmed/28983111
http://dx.doi.org/10.1038/s41598-017-13082-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629255/
https://www.ncbi.nlm.nih.gov/pubmed/28983111
http://dx.doi.org/10.1038/s41598-017-13082-z

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