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Paclitaxel induces Stathmin 1 phosphorylation, microtubule stability and apoptosis in acute lymphoblastic leukemia cells

Acute lymphoblastic leukemia (ALL) is a hematological malignancy characterized by abnormal proliferation and accumulation of lymphoblasts in the hematopoietic system. Stathmin 1 is a proliferation marker for normal lymphocytes, which has been described as highly expressed in ALL patients and functio...

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Detalles Bibliográficos
Autores principales: Machado-Neto, João Agostinho, Rodrigues Alves, Ana Paula Nunes, Fernandes, Jaqueline Cristina, Coelho-Silva, Juan Luiz, Scopim-Ribeiro, Renata, Fenerich, Bruna Alves, da Silva, Fernanda Borges, Scheucher, Priscila Santos, Simões, Belinda Pinto, Rego, Eduardo Magalhães, Traina, Fabiola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629349/
https://www.ncbi.nlm.nih.gov/pubmed/29034341
http://dx.doi.org/10.1016/j.heliyon.2017.e00405