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RUNX3 is oncogenic in natural killer/T-cell lymphoma and is transcriptionally regulated by MYC
RUNX3, runt-domain transcription factor, is a master regulator of gene expression in major developmental pathways. It acts as a tumor suppressor in many cancers but is oncogenic in certain tumors. We observed upregulation of RUNX3 mRNA and protein expression in nasal-type extranodal natural killer (...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629367/ https://www.ncbi.nlm.nih.gov/pubmed/28119527 http://dx.doi.org/10.1038/leu.2017.40 |