Cargando…

Roles of alternative splicing in modulating transcriptional regulation

BACKGROUND: The ability of a transcription factor to regulate its targets is modulated by a variety of genetic and epigenetic mechanisms. Alternative splicing can modulate gene function by adding or removing certain protein domains, and therefore affect the activity of protein. Reverse engineering o...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Jin, Wang, Yang, Rao, Xi, Wang, Yue, Feng, Weixing, Liang, Hong, Liu, Yunlong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629561/
https://www.ncbi.nlm.nih.gov/pubmed/28984199
http://dx.doi.org/10.1186/s12918-017-0465-6