Robust mutant strain design by pessimistic optimization

BACKGROUND: Flux Balance Analysis (FBA) based mathematical modeling enables in silico prediction of systems behavior for genome-scale metabolic networks. Computational methods have been derived in the FBA framework to solve bi-level optimization for deriving “optimal” mutant microbial strains with t...

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Detalles Bibliográficos
Autores principales: Apaydin, Meltem, Xu, Liang, Zeng, Bo, Qian, Xiaoning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629566/
https://www.ncbi.nlm.nih.gov/pubmed/28984191
http://dx.doi.org/10.1186/s12864-017-4025-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629566/
https://www.ncbi.nlm.nih.gov/pubmed/28984191
http://dx.doi.org/10.1186/s12864-017-4025-7

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