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N-Terminal Pfs230 Domain Produced in Baculovirus as a Biological Active Transmission-Blocking Vaccine Candidate

Transmission-blocking vaccines have the potential to accelerate malaria parasite elimination by inducing antibodies that block parasite transmission from humans to mosquitoes. Pfs230, a gametocyte surface protein involved in gamete function, has long been a promising candidate. Due to the large size...

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Detalles Bibliográficos
Autores principales: Lee, Shwu-Maan, Wu, Chia-Kuei, Plieskatt, Jordan L., Miura, Kazutoyo, Hickey, John M., King, C. Richter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629673/
https://www.ncbi.nlm.nih.gov/pubmed/28747311
http://dx.doi.org/10.1128/CVI.00140-17