Cargando…

FUT8 promotes breast cancer cell invasiveness by remodeling TGF-β receptor core fucosylation

BACKGROUND: Core fucosylation (addition of fucose in α-1,6-linkage to core N-acetylglucosamine of N-glycans) catalyzed by fucosyltransferase 8 (FUT8) is critical for signaling receptors involved in many physiological and pathological processes such as cell growth, adhesion, and tumor metastasis. Tra...

Descripción completa

Detalles Bibliográficos
Autores principales: Tu, Cheng-Fen, Wu, Meng-Ying, Lin, Yuh-Charn, Kannagi, Reiji, Yang, Ruey-Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629780/
https://www.ncbi.nlm.nih.gov/pubmed/28982386
http://dx.doi.org/10.1186/s13058-017-0904-8