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FUT8 promotes breast cancer cell invasiveness by remodeling TGF-β receptor core fucosylation
BACKGROUND: Core fucosylation (addition of fucose in α-1,6-linkage to core N-acetylglucosamine of N-glycans) catalyzed by fucosyltransferase 8 (FUT8) is critical for signaling receptors involved in many physiological and pathological processes such as cell growth, adhesion, and tumor metastasis. Tra...
Autores principales: | Tu, Cheng-Fen, Wu, Meng-Ying, Lin, Yuh-Charn, Kannagi, Reiji, Yang, Ruey-Bing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629780/ https://www.ncbi.nlm.nih.gov/pubmed/28982386 http://dx.doi.org/10.1186/s13058-017-0904-8 |
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