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Revisiting Escherichia coli as microbial factory for enhanced production of human serum albumin

BACKGROUND: Human serum albumin (HSA)—one of the most demanded therapeutic proteins with immense biotechnological applications—is a large multidomain protein containing 17 disulfide bonds. The current source of HSA is human blood plasma which is a limited and unsafe source. Thus, there exists an ind...

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Detalles Bibliográficos
Autores principales: Sharma, Ashima, Chaudhuri, Tapan K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629808/
https://www.ncbi.nlm.nih.gov/pubmed/28982367
http://dx.doi.org/10.1186/s12934-017-0784-8