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Association between habenula dysfunction and motivational symptoms in unmedicated major depressive disorder

The lateral habenula plays a central role in reward and punishment processing and has been suggested to drive the cardinal symptom of anhedonia in depression. This hypothesis is largely based on observations of habenula hypermetabolism in animal models of depression, but the activity of habenula and...

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Detalles Bibliográficos
Autores principales: Liu, Wen-Hua, Valton, Vincent, Wang, Ling-Zhi, Zhu, Yu-Hua, Roiser, Jonathan P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629818/
https://www.ncbi.nlm.nih.gov/pubmed/28575424
http://dx.doi.org/10.1093/scan/nsx074