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Association between habenula dysfunction and motivational symptoms in unmedicated major depressive disorder
The lateral habenula plays a central role in reward and punishment processing and has been suggested to drive the cardinal symptom of anhedonia in depression. This hypothesis is largely based on observations of habenula hypermetabolism in animal models of depression, but the activity of habenula and...
Autores principales: | Liu, Wen-Hua, Valton, Vincent, Wang, Ling-Zhi, Zhu, Yu-Hua, Roiser, Jonathan P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629818/ https://www.ncbi.nlm.nih.gov/pubmed/28575424 http://dx.doi.org/10.1093/scan/nsx074 |
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