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Switches in Genomic GC Content Drive Shifts of Optimal Codons under Sustained Selection on Synonymous Sites

The major codon preference model suggests that codons read by tRNAs in high concentrations are preferentially utilized in highly expressed genes. However, the identity of the optimal codons differs between species although the forces driving such changes are poorly understood. We suggest that these...

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Detalles Bibliográficos
Autores principales: Sun, Yu, Tamarit, Daniel, Andersson, Siv G.E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629928/
https://www.ncbi.nlm.nih.gov/pubmed/27540085
http://dx.doi.org/10.1093/gbe/evw201