Microarray analysis of bone marrow lesions in osteoarthritis demonstrates upregulation of genes implicated in osteochondral turnover, neurogenesis and inflammation

OBJECTIVE: Bone marrow lesions (BMLs) are well described in osteoarthritis (OA) using MRI and are associated with pain, but little is known about their pathological characteristics and gene expression. We evaluated BMLs using novel tissue analysis tools to gain a deeper understanding of their cellul...

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Detalles Bibliográficos
Autores principales: Kuttapitiya, Anasuya, Assi, Lena, Laing, Ken, Hing, Caroline, Mitchell, Philip, Whitley, Guy, Harrison, Abiola, Howe, Franklyn A, Ejindu, Vivian, Heron, Christine, Sofat, Nidhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2017
Materias:
Basic and Translational Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629942/
https://www.ncbi.nlm.nih.gov/pubmed/28705915
http://dx.doi.org/10.1136/annrheumdis-2017-211396

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629942/
https://www.ncbi.nlm.nih.gov/pubmed/28705915
http://dx.doi.org/10.1136/annrheumdis-2017-211396

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