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H1N1 vaccination in Sjögren’s syndrome triggers polyclonal B cell activation and promotes autoantibody production

OBJECTIVES: Vaccination of patients with rheumatic disease has been reported to result in lower antibody titres than in healthy individuals. However, studies primarily include patients on immunosuppressive therapy. Here, we investigated the immune response of treatment-naïve patients diagnosed with...

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Detalles Bibliográficos
Autores principales: Brauner, Susanna, Folkersen, Lasse, Kvarnström, Marika, Meisgen, Sabrina, Petersen, Sven, Franzén-Malmros, Michaela, Mofors, Johannes, Brokstad, Karl A, Klareskog, Lars, Jonsson, Roland, Westerberg, Lisa S, Trollmo, Christina, Malmström, Vivianne, Ambrosi, Aurelie, Kuchroo, Vijay K, Nordmark, Gunnel, Wahren-Herlenius, Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629946/
https://www.ncbi.nlm.nih.gov/pubmed/28760805
http://dx.doi.org/10.1136/annrheumdis-2016-210509