Transposable elements are the primary source of novelty in primate gene regulation

Gene regulation shapes the evolution of phenotypic diversity. We investigated the evolution of liver promoters and enhancers in six primate species using ChIP-seq (H3K27ac and H3K4me1) to profile cis-regulatory elements (CREs) and using RNA-seq to characterize gene expression in the same individuals...

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Detalles Bibliográficos
Autores principales: Trizzino, Marco, Park, YoSon, Holsbach-Beltrame, Marcia, Aracena, Katherine, Mika, Katelyn, Caliskan, Minal, Perry, George H., Lynch, Vincent J., Brown, Christopher D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630026/
https://www.ncbi.nlm.nih.gov/pubmed/28855262
http://dx.doi.org/10.1101/gr.218149.116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630026/
https://www.ncbi.nlm.nih.gov/pubmed/28855262
http://dx.doi.org/10.1101/gr.218149.116

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