Discovering novel pharmacogenomic biomarkers by imputing drug response in cancer patients from large genomics studies

Obtaining accurate drug response data in large cohorts of cancer patients is very challenging; thus, most cancer pharmacogenomics discovery is conducted in preclinical studies, typically using cell lines and mouse models. However, these platforms suffer from serious limitations, including small samp...

Descripción completa

Detalles Bibliográficos
Autores principales: Geeleher, Paul, Zhang, Zhenyu, Wang, Fan, Gruener, Robert F., Nath, Aritro, Morrison, Gladys, Bhutra, Steven, Grossman, Robert L., Huang, R. Stephanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630037/
https://www.ncbi.nlm.nih.gov/pubmed/28847918
http://dx.doi.org/10.1101/gr.221077.117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630037/
https://www.ncbi.nlm.nih.gov/pubmed/28847918
http://dx.doi.org/10.1101/gr.221077.117

Ejemplares similares