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Discovering novel pharmacogenomic biomarkers by imputing drug response in cancer patients from large genomics studies
Obtaining accurate drug response data in large cohorts of cancer patients is very challenging; thus, most cancer pharmacogenomics discovery is conducted in preclinical studies, typically using cell lines and mouse models. However, these platforms suffer from serious limitations, including small samp...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory Press
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630037/ https://www.ncbi.nlm.nih.gov/pubmed/28847918 http://dx.doi.org/10.1101/gr.221077.117 |