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Anti-proliferative Effect of C3 Exoenzyme in Fibroblasts is Mediated by c-Jun Phosphorylation

The ADP-ribosyltransferase C3 exoenzyme from C. botulinum selectively inactivates Rho and is therefore often used as an inhibitor for investigations on Rho signaling. Previous studies of our group revealed that C3 inhibited cell proliferation in HT22 cells accompanied by increased transcriptional ac...

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Detalles Bibliográficos
Autores principales: von Elsner, Leonie, Hagemann, Sandra, Just, Ingo, Rohrbeck, Astrid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ubiquity Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630077/
https://www.ncbi.nlm.nih.gov/pubmed/30210577
http://dx.doi.org/10.5334/1750-2187-12-1