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Sequence features of viral and human Internal Ribosome Entry Sites predictive of their activity
Translation of mRNAs through Internal Ribosome Entry Sites (IRESs) has emerged as a prominent mechanism of cellular and viral initiation. It supports cap-independent translation of select cellular genes under normal conditions, and in conditions when cap-dependent translation is inhibited. IRES stru...
Autores principales: | Gritsenko, Alexey A., Weingarten-Gabbay, Shira, Elias-Kirma, Shani, Nir, Ronit, de Ridder, Dick, Segal, Eran |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630158/ https://www.ncbi.nlm.nih.gov/pubmed/28922394 http://dx.doi.org/10.1371/journal.pcbi.1005734 |
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