Exome sequencing analysis of murine medulloblastoma models identifies WDR11 as a potential tumor suppressor in Group 3 tumors

Mouse models of human cancers are widely used in cancer research, yet questions frequently arise regarding their faithfulness in recapitulating their human counterparts. To compare the somatic mutations of murine models with human medulloblastoma (MB), we performed whole-exome sequencing on 12 tumor...

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Detalles Bibliográficos
Autores principales: Wei, Lei, Murphy, Brian L., Wu, Gang, Parker, Matthew, Easton, John, Gilbertson, Richard J., Zhang, Jinghui, Roussel, Martine F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Priority Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630286/
https://www.ncbi.nlm.nih.gov/pubmed/29029386
http://dx.doi.org/10.18632/oncotarget.19642

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630286/
https://www.ncbi.nlm.nih.gov/pubmed/29029386
http://dx.doi.org/10.18632/oncotarget.19642

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