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RASAL1 is a potent regulator of hepatic stellate cell activity and liver fibrosis

Liver fibrosis, leading to cirrhosis and liver failure, can occur after chronic liver injury. The transition of hepatic stellate cells (HSCs) from quiescent cells into proliferative and fibrogenic cells is a central event in liver fibrosis. Here, we show that RAS protein activator like-1 (RASAL1), a...

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Detalles Bibliográficos
Autores principales: Takata, Akemi, Otsuka, Motoyuki, Kishikawa, Takahiro, Yamagami, Mari, Ishibashi, Rei, Sekiba, Kazuma, Suzuki, Tatsunori, Ohno, Motoko, Yamashita, Yui, Abe, Takaya, Masuzaki, Ryota, Ikenoue, Tsuneo, Koike, Kazuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630295/
https://www.ncbi.nlm.nih.gov/pubmed/29029395
http://dx.doi.org/10.18632/oncotarget.17609