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RASAL1 is a potent regulator of hepatic stellate cell activity and liver fibrosis
Liver fibrosis, leading to cirrhosis and liver failure, can occur after chronic liver injury. The transition of hepatic stellate cells (HSCs) from quiescent cells into proliferative and fibrogenic cells is a central event in liver fibrosis. Here, we show that RAS protein activator like-1 (RASAL1), a...
Autores principales: | Takata, Akemi, Otsuka, Motoyuki, Kishikawa, Takahiro, Yamagami, Mari, Ishibashi, Rei, Sekiba, Kazuma, Suzuki, Tatsunori, Ohno, Motoko, Yamashita, Yui, Abe, Takaya, Masuzaki, Ryota, Ikenoue, Tsuneo, Koike, Kazuhiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630295/ https://www.ncbi.nlm.nih.gov/pubmed/29029395 http://dx.doi.org/10.18632/oncotarget.17609 |
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