A cellular platform for the evaluation of immune checkpoint molecules

Blockade of the T cell coinhibitory molecules CTLA-4 and PD-1 has clinical utility to strengthen T cell responses. In addition to these immune checkpoints an ever-growing number of molecules has been implicated in generating coinhibitory signals in T cells. However, investigating coinhibitory molecu...

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Detalles Bibliográficos
Autores principales: Jutz, Sabrina, Hennig, Annika, Paster, Wolfgang, Asrak, Ömer, Dijanovic, Dejana, Kellner, Florian, Pickl, Winfried F., Huppa, Johannes B., Leitner, Judith, Steinberger, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper: Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630299/
https://www.ncbi.nlm.nih.gov/pubmed/29029399
http://dx.doi.org/10.18632/oncotarget.17615

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630299/
https://www.ncbi.nlm.nih.gov/pubmed/29029399
http://dx.doi.org/10.18632/oncotarget.17615

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